The Mega Millions prizes start from $2 for matching the Mega Ball only and escalate up to the Jackpot won when players reach the five main numbers and the Mega Ball. The overall odds of winning any prize in the Mega Millions lottery are 1 in 24. The prize structure of Mega Millions below can help you calculate the odds of winning the lottery. Don’t worry if you didn’t match all six MultiState Mega Millions winning numbers. There are 9 ways to win in Mega Millions. Click on Mega Millions Prizes and Payout Chart to know how.