Alcohol-based hand sanitizer react with COVID-19 by dissolving the fatty outside layer of the virus and damage the structures of the virus proteins. This FDA approved formulation for a Hand Sanitizer – Liquid meets all the guidelines to attack Coronavirus (COVID-19) and many other germs. Sanitizing hands or a hard surface refers to lowering the number of germs to a safe level. Alcohol-based sanitizers react with COVID-19 (SARS-CoV-2) by dissolving the fatty outside layer of the virus and damage the structures of the virus proteins.