The effects of Cenforce 25 typically last for about 4-6 hours, during which time you may find it easier to achieve and maintain an erection when sexually aroused. Do not exceed the recommended dosage: Taking more than the recommended dose does not increase the effectiveness of the medication but can lead to an increased risk of side effects. ED is a common condition in which a man has difficulty achieving or maintaining an erection sufficient for sexual activity. It can be caused by various factors, including physical, psychological, and lifestyle-related issues.