While Filitra may help with ED and has some mild blood pressure-lowering effects, it should be used cautiously in men who are already on blood pressure medications. Vardenafil can interact with nitrate medications (commonly used to treat chest pain) and cause a dangerous drop in blood pressure. Therefore, men with hypertension should consult their doctor before using Filitra, especially if they are on medications such as nitrates, alpha-blockers, or other antihypertensive drugs.