Mannitol spheres are a distinct type of sphere formed from the sugar alcohol mannitol. Mannitol, which is produced by MB Sugars, is used in tablets and capsules as a filler or binder. It can also be utilized for pharmaceutical and nutraceutical products in a variety of oral dose forms.

Mannitol is a good substrate for diluent combinations in tablet, pill, and powder formulations due to its non-hygroscopic characteristics and agreeable, bland flavor.