Pregabalin 300 mg is a pain-relieving medication that works by inhibiting the activity of certain neurotransmitters in the brain and spinal cord that are involved in pain signaling. The Food and Drug Administration (FDA) has approved it for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and spinal cord injury. It is also approved for fibromyalgia treatment.