Berberine PCOS is a potent insulin sensitiser, equal to that of metformin. In one study, after 3 months of treatment, women who took berberine saw greater reductions in body fat loss than metformin or placebo. Additionally, berberine lowered insulin and glucose levels similarly to metformin, but significantly reduced total cholesterol and triglycerides, and improved HDL more so than metformin. Visit us to buy now.